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We interviewed Dr. Rajan George, Adjunct Faculty of the University of Alberta's Pharmacy and Pharmaceutical Sciences Department. Dr. George is also Vice President of Research and Development for the Division of Infection Diseases of ViRexx Medical Co. As part of the team of University of Alberta scientists Wholesale Nike Air Max 95 Trainers UK , a therapeutic vaccine is now being developed which may inoculate against Hepatitis, Anthrax and Avian Flu H5N1. The team of scientists includes internationally renowned Dr. Lorne Tyrrell, former Dean of Medicine at the University of Alberta, and Dr. Antoine Noujaim Wholesale Nike Air Max 95 UK China , Professor Emeritus of the University of Alberta.
All three scientists are affiliated with ViRexx Medical Corp. On March 31st, the company announced it had entered into research collaboration with Defence Research and Development Canada - Suffield (DRDC Suffield) to carry out research to evaluate ViRexx's proprietary Chimigen? vaccine platform for biodefense applications. On April 6th, the company announced it had recruited procurement advocate Frank Rapoport of McKenna Long & Aldridge to pursue acquisitions of development contracts from the U.S. Department of Defense and NIH with a particular focus on the potential of the Chimigen? technology in addressing biodefense and pandemic threats. The company cited two of major targets would be, but not limited to Wholesale Nike Air Max 95 UK Online , H5N1 avian flu and anthrax.
Interviewer: Can you describe ViRexx Medical's Chimigen? therapeutic vaccine?
Dr. Rajan George: Chimigen therapeutic vaccine is used to produce immune responses in a host against infections which are difficult to produce immune responses, by targeting the vaccine to dendritic cells. The Chimigen platform can be extended to develop therapies for difficult-to-treat chronic infectious diseases.
Interviewer: Does that mean the Chimigen platform can be used to treat any infectious disease?
Dr. Rajan George: Yes, except in cases where the immune system is non-functional, as in the case of Chimigen platform can be used to produce either a therapeutic vaccine or a prophylactic vaccine. This depends on the disease target and the antigen plugged into the platform. Some antigens have a use in treating infection Wholesale Nike Air Max 95 Youth UK , while others have a use in preventing an infection. Either one would be targeted to the dendritic cells. The therapeutic vaccine generates a cytotoxic T cell response. A prophylactic vaccine would generate a B cell response and antibody production.
Interviewer: From the way you've described the Chimigen? vaccine, it appears potentially useful for many applications beyond Hepatitis B and C. How broad are the applications?
Dr. Rajan George: We should be able to use this platform for cancer therapy, depending upon the cancer antigen we use. We can plug in a specific cancer antigen into this platform, and the vaccine targeted to dendritic cells. The dendritic cells would process and present the right antigen Wholesale Nike Air Max 95 Womens UK , then generating immune responses (T &B cell) against the cancer. We are also evaluating some bioterrorist viruses, the biological weapons terrorists would use. We just started a project to look at one of those viruses to see if we can come up with the prophylactic vaccines to prevent diseases that would be caused by organism that could be used in bioterrorism
Interviewer: Would the Chimigen? vaccine be effective as a prophylactic against avian flu, H5N1?